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nastaran hashemi

    News and Announcements

Catherine Meis Named a 2015 Goldwater Scholar
Iowa State University student Catherine Meis, Le Catie Meis Goldwater Montazami HashemiMars, has been named a 2015 Goldwater Scholar, the nation's premier undergraduate scholarship in mathematics, natural sciences and engineering. Meis is a third-year student, majoring in materials engineering with a minor in bioengineering.  (Full Story)


Jeremy Caplin Selected for 2015 NSF East Asia and Pacific Summer Institutes Fellowship
The National Science Foundation (NSF) East Asia and PaciJeremy NSF EAPSIfic Summer Institutes (EAPSI) recently announced the Fellows selected for its summer program designed to promote international, collaborative research projects in Asia. Mechanical engineering graduate student Jeremy Caplin was one of the students chosen for the honor. His research at Iowa State focuses on developing and designing a “placenta-on-a-chip,” which utilizes human cell lines to mimic the nutrient and waste transfer between a mother and fetus in the placenta. (Full Story)

Hashemi invited to deliver a keynote presentation at the ASME ICNMM 2014
Nastaran Hashemi is invited to deliver a keynote presentation at the ASME 2014 Joint US-European Fluids Engineering Division Summer Meeting and the International Conference on Nanochannels, Microchannels, and Minichannels. (Keynote presentation at the ASME)

On-Chip Development of Hydrogel Microfibers from Round to Square/Ribbon-Shaped

microfibersOur hydrogel microfibers manuscript has been published in the Journal of Materials Chemistry A. We use a microfluidic approach to fabricate gelatin microfibers with controlled sizes and cross sections.





Hashemi invited to attend NAS symposium
Nastaran Hashemi, William March Scholar in Mechanical Engineering and assistant professor, has been invited to attend the National Academy of Sciences Indo-American Frontiers in Science, being held April 7-10, in Agra, India. The symposium is designed to create a collaborative environment by bringing together outstanding young scientists from diverse disciplines to share their research.
(
NAS invitation release)

Hashemi receives NRC/ASEE research publication award for optofluidic approach

Nastaran Hashemi, William March Scholar in Mechanical Engineering, was chosen to receive the 2011 Naval Research Laboratory NRC/ASEE Research Publication Award for her paper “Optofluidic characterization of marine algae using a microflow cytometer.” (Hashemi publication award release)

 hashemi

Pursuing New Ideasbirutawit
Being the William March Scholar in Mechanical Engineering at Iowa State University is much more than just a prestigious title. Nastaran Hashemi was named the latest March Scholar this past fall, and she has hit the ground running with the funding that the award provides her. (Full story)

 

Microfluidic Organ-on-a-Chip Technology for Advancement of Drug
Development and Toxicology

In Jeremy Caplin's recent publorgan chip hashemi montazamiication in Advanced Healthcare Materials, a systematic approach is taken to review current technologies pertaining to organ-on-a-chip systems. Design processes with attention to the particular instruments, cells, and materials used are presented. Before a new drug is released in the market it must go through intensive testing; prior to approval for human testing, most drugs first need to be tested for safety through animal testing. The use of animals in such experiments is often expensive, time consuming, ethically controversial, and is often an inaccurate representation of actual human response. Organ-on-a-chip technology provides a practical solution to many of the issues presented by both two-dimensional models and animal testing.
 
Research Interests
Microfluidics
Biosensors
Optofluidics
Materials
Renewable Energy
Lab on a Chip
Diagnostics and Therapeutics
Physics of Micro/Nanoscale Phenomena

At the Hashemi Lab, we are working on projects concerned with the design and fabrication of microfluidic/optofluidic devices with applications to clinical diagnosis, renewable energy, and environmental monitoring.

Our primary research objective is to understand how microfluidic transport could provide a fundamental science base for novel fabrication of polymer microfibers with controlled size, shape, and molecular alignment. Computational fluid dynamics and experimental techniques will be employed to design and study characteristics of highly structured microfibers.

Also, hydrodynamic focusing of one laminar stream by another has inspired new approaches in biosensors and cell analysis. We have devised a novel system to ensheathe, focus, and separate the sample stream from the sheath streams. Using grooves at very specific orientations in the upper and lower surfaces of the microchannel, the sheath fluid is directed around the sample stream in the microflow cytometer. The dynamics of fluid flow can be reversed by reversing the direction of the forces applied to the system at low Reynolds number. Integrating the concept of “unstirring” into the groove-based sheath flow system by placing reverse grooves in the channel pointing upstream, the sample stream is separated from the contiguous sheath streams. The unsheathing capability provides the opportunity to recover particles from the sensor with minimal dilution or to recycle the sheath fluid for long-term unattended operation.

Adult Hippocampal Progenitor Cells (AHPCs) grown 5 days in vitro on PCL
Microfibers


ahpc2
               
               

nastaran@iastate.edu
2028 Black Engineering Building