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Optofluidic Systems
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nastaran hashemi

    News and Announcements

Invited speaker at World Preclinical Congress
Prof. Hashemi will be delivering an invited talk at the 3D Cellular Models meeting in Boston in June 2016.

Hashemi to give seminar at University of TorontoNastaran Hashemi Professor
Prof. Hashemi is giving an invited seminar at the University of Toronto in the Department of Mechanical and Industrial Engineering on
November 20, 2015. (Seminar Series)

Catherine Meis named a 2015 Goldwater Scholar

Iowa State University student Catherine Meis, LeCatie Meis Goldwater Montazami Hashemi Mars, has been named a 2015 Goldwater Scholar, the nation's premier undergraduate scholarship in mathematics, natural sciences and engineering. (Full Story)

Jeremy Caplin selected as a 2015 NSF EAPSI Fellow
The National Science Foundation (NSF) East Asia and PaciJeremy NSF EAPSIfic Summer Institutes (EAPSI) recently announced the Fellows selected for its summer program designed to promote international, collaborative research projects in Asia. Mechanical engineering graduate student Jeremy Caplin was one of the students chosen for the honor. His research at Iowa State focuses on developing and designing a “placenta-on-a-chip". (Full Story)

Microfluidic organ-on-a-chip technology for advancement of drug development and toxicology
In Jeremy Caplin's recent publication in Advanced Horgan chip hashemi montazamiealthcare Materials, a systematic approach is taken to review current technologies pertaining to organ-on-a-chip systems. Organ-on-a-chip technology provides a practical solution to many of the issues presented by both two-dimensional models and animal testing.

Keynote presentation at the ASME ICNMM 2014
Nastaran Hashemi is invited to deliver a keynote presentation at the ASME 2014 Joint US-European Fluids Engineering Division Summer Meeting and the International Conference on Nanochannels, Microchannels, and Minichannels. (ASME keynote presentation)

Hashemi invited to attend NAS symposium
Nastaran Hashemi, William March Scholar in Mechanical Engineering and assistant professor, has been invited to attend the National Academy of Sciences Indo-American Frontiers in Science, being held April 7-10, in Agra, India. The symposium is designed to create a collaborative environment by bringing together outstanding young scientists from diverse disciplines to share their research.
(NAS invitation release)

Hashemi receives NRC/ASEE research publication award for optofluidic approach

Nastaran Hashemi, William March Scholar in Mechanical Engineering, was chosen to receive the 2011 Naval Research Laboratory NRC/ASEE Research Publication Award for her paper “Optofluidic characterization of marine algae using a microflow cytometer.” (Hashemi publication award release)



Research Interests
Lab on a Chip
Diagnostics and Therapeutics
Renewable Energy
Physics of Micro/Nanoscale Phenomena

At the Hashemi Lab, we are working on projects concerned with the design and fabrication of microfluidic/optofluidic devices with applications to clinical diagnosis, renewable energy, and environmental monitoring.

Our primary research objective is to understand how microfluidic transport could provide a fundamental science base for novel fabrication of polymer microfibers with controlled size, shape, and molecular alignment. Computational fluid dynamics and experimental techniques will be employed to design and study characteristics of highly structured microfibers.

Also, hydrodynamic focusing of one laminar stream by another has inspired new approaches in biosensors and cell analysis. We have devised a novel system to ensheathe, focus, and separate the sample stream from the sheath streams. Using grooves at very specific orientations in the upper and lower surfaces of the microchannel, the sheath fluid is directed around the sample stream in the microflow cytometer. The dynamics of fluid flow can be reversed by reversing the direction of the forces applied to the system at low Reynolds number. Integrating the concept of “unstirring” into the groove-based sheath flow system by placing reverse grooves in the channel pointing upstream, the sample stream is separated from the contiguous sheath streams. The unsheathing capability provides the opportunity to recover particles from the sensor with minimal dilution or to recycle the sheath fluid for long-term unattended operation.

Fabrication of polymer microfibers with controlled sizes and cross sections using microfluidic approach


Adult Hippocampal Progenitor Cells (AHPCs) grown 5 days in vitro on PCL


2028 Black Engineering Building